Endocrine Abstracts

Background: Lead is known as an environmental toxic pollutant and hormonal regulatory confounder associated with obesity. Recent China scientific report shows that blood lead level (BLL) is closely related with body mass index. Therefore, we investigated the association between the prevalence of metabolic syndrome and blood lead levels in healthy general population without hypertension, dyslipidemia, and diabetes.Methods: We assessed the socio-demographi...

Recently, dipeptidyl peptidase-IV (DPP-IV) inhibitor, a major anti-hyperglycaemic agent, has received substantial attention as a possible therapeutic target for inflammatory diseases such as atherosclerosis. However, the direct molecular mechanisms through which DPP-IV inhibitor mediates anti-inflammatory effects in vascular endothelial cells have not been clarified. The effects of the DPP-IV inhibitor, gemigliptin, were analysed in human umbilical vein endothelial cells (HUVE...